ZC3H12A |
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بنى متوفرة |
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بنك بيانات البروتين | Ortholog search: PDBe RCSB | قائمة رموز معرفات بنك بيانات البروتين | 3V32, 3V33, 3V34 | | |
معرفات |
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أسماء بديلة | ZC3H12A, MCPIP, MCPIP1, dJ423B22.1, zinc finger CCCH-type containing 12A, Reg1, MCPIP-1 |
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معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 610562 MGI: MGI:2385891 HomoloGene: 11824 GeneCards: 80149 |
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علم الوجود الجيني |
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وظائف جزيئية | • miRNA binding • chromatin binding • ربط أيون فلزي • ribonuclease activity • GO:0001948، GO:0016582 ربط بروتيني • nuclease activity • endonuclease activity • mRNA binding • نشاط هيدرولاز • ribosome binding • mRNA 3'-UTR binding • mRNA 3'-UTR AU-rich region binding • ربط دي إن إي • RNA binding • endoribonuclease activity • exoribonuclease activity • thiol-dependent deubiquitinase • RNA stem-loop binding |
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مكونات خلوية | • سيتوبلازم • بلازم نووي • هيكل خلوي • نواة • extrinsic component of endoplasmic reticulum membrane • شبكة إندوبلازمية • rough endoplasmic reticulum membrane • rough endoplasmic reticulum • أجسام P • غشاء • حبيبة رنا • GO:0009327 protein-containing complex |
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عمليات حيوية | • positive regulation of p38MAPK cascade • cellular response to virus • تمايز خلوي • positive regulation of cell death • positive regulation of autophagy • negative regulation of interleukin-6 production • positive regulation of lipid storage • negative regulation of macrophage activation • cellular response to tumor necrosis factor • negative regulation of gene expression • positive regulation of angiogenesis • negative regulation of production of miRNAs involved in gene silencing by miRNA • positive regulation of endothelial cell migration • نمو متعدد الخلايا • protein deubiquitination • GO:1901313 positive regulation of gene expression • positive regulation of reactive oxygen species metabolic process • protein complex oligomerization • توليد الأوعية • تنظيم التعبير الجيني • positive regulation of protein import into nucleus • negative regulation by host of viral genome replication • negative regulation of tumor necrosis factor production • positive regulation of miRNA catabolic process • negative regulation of NF-kappaB transcription factor activity • positive regulation of defense response to virus by host • GO:0097285 استماتة • RNA phosphodiester bond hydrolysis, endonucleolytic • immune system process • negative regulation of muscle cell apoptotic process • negative regulation of I-kappaB kinase/NF-kappaB signaling • نسخ الدنا • positive regulation of fat cell differentiation • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني • nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay • defense response to virus • cellular response to glucose starvation • نماء عصبي • negative regulation of cytokine production involved in inflammatory response • cellular response to sodium arsenite • GO:0009373 ضبط نسخ الدنا • GO:0033128 negative regulation of protein phosphorylation • cellular response to ionomycin • positive regulation of mRNA catabolic process • cellular response to lipopolysaccharide • cellular response to oxidative stress • RNA phosphodiester bond hydrolysis • negative regulation of nitric oxide biosynthetic process • cellular response to interleukin-1 • positive regulation of protein deubiquitination • cellular response to chemokine • inflammatory response • 3'-UTR-mediated mRNA destabilization • negative regulation of cardiac muscle contraction • positive regulation of execution phase of apoptosis • RNA phosphodiester bond hydrolysis, exonucleolytic • cellular response to DNA damage stimulus • immune response-activating signal transduction • negative regulation of NIK/NF-kappaB signaling • T cell receptor signaling pathway • negative regulation of T-helper 17 cell differentiation |
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المصادر:Amigo / QuickGO | |
تماثلات متسلسلة |
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أنواع | الإنسان | الفأر |
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أنتريه | 80149 | 230738 |
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Ensembl | ENSG00000163874 | ENSMUSG00000042677 |
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يونيبروت | | |
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RefSeq (رنا مرسال.) | | NM_025079، NM_001323550، NM_001323551، XM_047430884، XM_047430885، XM_047430886 XM_011542198، NM_025079، NM_001323550، NM_001323551، XM_047430884، XM_047430885، XM_047430886 |
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RefSeq (بروتين) | | NP_001310480، NP_079355، XP_011540500 NP_001310479، NP_001310480، NP_079355، XP_011540500 |
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الموقع (UCSC | n/a | Chr 4: 125.01 – 125.02 Mb |
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بحث ببمد | [1] | [2] |
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ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
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