Deserpidine

Deserpidine
Names
IUPAC name
methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8-tetraene-19-carboxylate
Identifiers
CAS Number
  • 131-01-1 ☑Y
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:27478 ☑Y
ChEMBL
  • ChEMBL1200515 ☒N
ChemSpider
  • 8232 ☑Y
DrugBank
  • DB01089 ☑Y
ECHA InfoCard 100.004.551
IUPHAR/BPS
  • 7064
KEGG
  • D08194 ☑Y
PubChem <abbr title="<nowiki>Compound ID</nowiki>">CID
  • 8550
UNII
  • 9016E3VB47 Lưu trữ 2016-03-03 tại Wayback Machine ☑Y
CompTox Dashboard (<abbr title="<nowiki>U.S. Environmental Protection Agency</nowiki>">EPA)
  • DTXSID8020383 Edit this at Wikidata
InChI
  • InChI=1S/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1 ☑Y
    Key: CVBMAZKKCSYWQR-WCGOZPBSSA-N ☑Y
  • InChI=1/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1
    Key: CVBMAZKKCSYWQR-WCGOZPBSBL
SMILES
  • O=C(OC)[C@H]6[C@H]4C[C@@H]3c2[nH]c1ccccc1c2CCN3C[C@H]4C[C@@H](OC(=O)c5cc(OC)c(OC)c(OC)c5)[C@@H]6OC
Properties
Chemical formula
 C32H38N2O8
Molar mass 578.662 g·mol−1
Pharmacology
ATC code
 C02AA05 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Deserpidine (INN) là một loại thuốc hạ huyết áp liên quan đến reserpin [1] xuất hiện ở tự nhiên trong Rauvolfia spp.

Tham khảo

  1. ^ Fulton, S. C.; Healy, M. D. (1976). “Comparison of the effectiveness of deserpidine, reserpine, and alpha-methyltyrosine on brain biogenic amines”. Federation Proceedings. 35 (14): 2558–2562. PMID 11134.