Tymazoline

Chemical compound

R01AA13 (WHO)

Identifiers

IUPAC name

2-[(5-methyl-2-propan-2-ylphenoxy)methyl]-4,5-dihydro-1H-imidazole

CAS Number

24243-97-8^N

PubChem CID

34154

DrugBank

DB08803^Y

ChemSpider

31478^Y

UNII

U993RH5585

KEGG

D07373^N

CompTox Dashboard (EPA)

DTXSID40178939

Chemical and physical dataFormulaC₁₄H₂₀N₂OMolar mass232.327 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

Cc1ccc(c2c1cccc2OCC3=NCCN3)C(C)C

InChI

InChI=1S/C14H20N2O/c1-10(2)12-5-4-11(3)8-13(12)17-9-14-15-6-7-16-14/h4-5,8,10H,6-7,9H2,1-3H3,(H,15,16)^Y
Key:QRORCRWSRPKEHR-UHFFFAOYSA-N^Y

^NY (what is this?) (verify)

Tymazoline (trade name Thymazen in Poland) is a nasal decongestant that can be used to treat rhinitis. It acts as an antihistaminic and sympathomimetic, reducing swelling, inflammation and mucosal secretions.^[1]^[2]

References

^ Drugs.com: Tymazoline
^ DrugBank: Tymazoline

Decongestants and other nasal preparations (R01)

Topical

Sympathomimetics, plain	Cyclopentamine Ephedrine Epinephrine Fenoxazoline Levomethamphetamine Metizoline Naphazoline Oxymetazoline Phenylephrine Propylhexedrine Tetryzoline Tramazoline Tuaminoheptane Tymazoline Xylometazoline
Antiallergic agents, excluding corticosteroids	Spaglumic acid histamine antagonists (Levocabastine Antazoline Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid Nedocromil Azelastine Olopatadine Lodoxamide)
Corticosteroids	Beclometasone dipropionate Betamethasone^# Budesonide Ciclesonide Dexamethasone Flunisolide Fluticasone (Fluticasone furoate, Fluticasone propionate) Mometasone furoate Prednisolone^# Tixocortol Triamcinolone Triamcinolone acetonide
Other nasal preparations	Cafaminol Calcium hexamine thiocyanate Eucalyptus oil Framycetin Hexamidine Hyaluronan Ipratropium bromide Mupirocin Retinol Ritiometan Saline water
Combination products	Olopatadine/mometasone