Tiemonium iodide

Chemical compound

Identifiers

CAS Number

PubChem CID

ChemSpider

UNII

KEGG

CompTox Dashboard (EPA)

ECHA InfoCard100.005.106

Chemical and physical dataFormulaC₁₈H₂₄INO₂SMolar mass445.36 g·mol⁻¹3D model (JSmol)

InChI

InChI=1S/C18H24NO2S.HI/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;/h2-8,15,20H,9-14H2,1H3;1H/q+1;/p-1
Key:IOFXEUZPIIUQAG-UHFFFAOYSA-M

Tiemonium iodide is an antimuscarinic. It is poorly absorbed from the gut. The active moiety is tiemonium, a quaternary ammonium cation.^[1]

References

^ Scoular IT, Monks A, Burgess C, Turner P (1977). "Human studies on the bioavailability of a quaternary ammonium compounds, tiemonium iodide and tiemonium methosulphate". Current Medical Research and Opinion. 4 (10): 732–8. doi:10.1185/03007997609112009. PMID 1052164.

Drugs for functional gastrointestinal disorders (A03)

Drugs for
functional
bowel
disorders

Antimuscarinics

Tertiary amino group	Oxyphencyclimine Camylofin Mebeverine Trimebutine Rociverine Dicycloverine Dihexyverine Difemerine Piperidolate
Quaternary ammonium compounds	Benzilone Mepenzolate Pipenzolate Glycopyrronium Oxyphenonium Penthienate Methantheline Propantheline Otilonium Tridihexethyl Isopropamide Hexocyclium Poldine Bevonium Diphemanil Tiemonium Prifinium Timepidium Fenpiverinium