Thiazide-like diuretic
A thiazide-like diuretic is a sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but does not have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure. Examples include metolazone, chlorthalidone, and indapamide.[1]
References
- ^ Foye's Principles of Medicinal Chemistry. David Williams (ed.) (7th ed.). Philadelphia: LWW. 2012-03-16. ISBN 978-1-60913-345-0.
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Diuretics (C03)
(and etacrynic acid)
CA inhibitors (at PT) |
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Loop (Na-K-Cl at AL) |
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Thiazides (Na-Cl at DCT, Calcium-sparing) | |
Thiazide-likes (primarily DCT) |
ESC blockers | |
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Aldosterone antagonists |
(DCT and CD)
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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